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| Product Name: | Febuxostat | Cas No: | 144060-53-7 |
|---|---|---|---|
| Appearance: | White Powder | Assay: | 99% |
| Grade: | Pharmaceutical Grade | Usage: | Gout Treatment |
| High Light: | pharma grade steroids,pharmaceutical anabolic steroids |
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High Quality Febuxostat API Powder Cas No 144060-53-7 For Gout Treatment
Febuxostat is a new generation of xanthine oxidase inhibitor developed by Japanese company. It is used in the treatment of gout. Its structure is totally different from that of xanthine oxidase inhibitor developed 40 years ago. It is a new and efficient selective inhibitor of non purine xanthine oxidase. Xanthine oxidase is the key enzyme to promote the production of uric acid. Febuxostat can reduce the level of chemical Book uric acid in the blood of gout patients with hyperuricemia. The clinical research shows that the product is safe and effective. The product is metabolized through the liver and does not depend on renal excretion. Therefore, it is not necessary to reduce the dosage of febuxostat in patients with moderate to severe hepatorenal insufficiency. The dosage is 40 mg or 80 mg once a day. It is not recommended to treat gout patients without hyperuricemia. In February 2009, the U.S. Food and Drug Administration (FDA) approved febuxostat for the long-term treatment of gout hyperuricemia.
| CAS No. | 144060-53-7 |
| Molecular Formula | C16H16N2O3S |
| LogP | 3.72318 |
| PSA | 111.450 |
| Flash point | 278.3°C |
| Melting point | 238-239°(dec.) |
| Boiling point | 536.6±60.0 °C(Predicted) |
| Density | 1.31g/cm3 |
| Shelf life | 2 Years |
(1) the allopurinol only have inhibition to reduced the XOR, rather than cloth sutent XOR of
oxidation and reduced significantly inhibitory effect, more powerful, durable and its effect in
lowering uric acid;
(2) because allopurinol is a purine analogues, it is inevitable to affect the metabolism of other
enzymes involved in purine and pyridine metabolism.So in allopurinol treatment, you need to
repeat a large dose to maintain a high level of medication.It also leads to serious and even fatal
adverse reactions caused by drug accumulation.Instead of being a non-purine XOR inhibitor, it
has better security.
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