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| Product Name: | Triptorelin Acetate | Purity: | 99% |
|---|---|---|---|
| Appearance: | Lyophilized Powder | Usage: | Treating Prostate Cancer |
| Cas: | 57773-63-4 | Molecular Formula: | C64H82N18O13 |
| High Light: | steroid based hormones,human growth peptides |
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Triptorelin Acetate Peptide Steroid Hormones For Treating Prostate Cancer CAS 57773-63-4
Quick details:
Triptorelin Acetate Product Name:Triptorelin Acetate
Triptorelin Acetate Cas No.: 57773-63-4
Triptorelin Acetate Sequence: Glp-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2
Triptorelin Acetate Purity (HPLC): 98.0% min.
Triptorelin Acetate Appearance: White powder
Molecular Formula: C64H82N18O13
Molecular Weight: 1311.46
Single Impurity (HPLC): 1.0%max
Amino Acid Composition: ±10% of theoretical
Peptide Content (N%): ≥80.0%
Water Content(Karl Fischer): ≤6.0%
Triptorelin Acetate Acetate Content (HPIC): ≤15.0%
Triptorelin Acetate MS(ESI): Consistent
Triptorelin Acetate Mass Balance: 95.0~105.0%
Triptorelin Acetate Specific Rotation (20/D): -65.0～-75.0°(c=0.5 1%HAc)
Abstract
Triptorelin is a man-made form of a hormone that regulates many processes in the body. Triptorelin over stimulates the body's own production of certain hormones, which causes that production to shut down temporarily.
Triptorelin is used to treat the symptoms of prostate cancer. Triptorelin treats only the symptoms of prostate cancer and does not treat the cancer itself. Use any other medications your doctor has prescribed to best treat your condition.
Triptorelin may also be used for purposes not listed in this medication guide.
Although triptorelin is not for use by women, this medication can cause birth defects and should not be used by a woman who is pregnant or who may become pregnant.
Application
Triptorelin may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer, precocious puberty, estrogen-dependent conditions, and in assisted reproduction. Triptorelin is marketed under the brand names Decapeptyl and Diphereline and Gonapeptyl.
In the United States, it is sold by Watson as Trelstar.In Iran Triptorelin is marketed under the brand name Variopeptyl.In India, Dr. Reddy's Laboratories has launched recently Triptorelin under the brand name "Pamorelin LA". During the treatment of prostate cancer it does cause a surge of testosterone, known as a flare effect. In men a reduction of serum testosterone levels into the range normally seen after surgical castration occurs approximately two to four weeks after initiation of therapy.
COA
| Triptorelin GNRH Specifications | ||||
| Appearance | White powder | |||
| Appearance of solution | Transparent | |||
| Colour of solution | Colorless | |||
| pH | offer | |||
| Specific Optical Rotation (c=0.5,95%HAc) | -65.0~-75.0 | |||
| Purity(by HPLC) | ≥98.00%~99.90% | |||
| Total Impurities(by HPLC) | ≤2.00%~0.10% | |||
| Single Impurity(by HPLC) | ≤0.50%~0.03% | |||
| Water Content(Karl Fischer) | ≤4.80% | |||
| Acetate Content(by HPLC) | ≤6.80% | |||
| Peptide Content(by %N ) | ≥88.00% | |||
| Amino Acaid Composition | ±10% of theoretical | |||
| Assay(By anhydrous, acetic acid-free) | 95.0%~105.0% | |||
| Solubility | offer | |||
| storage | Normal store:2-8ºC Long-term storage:-20±5ºC |
Package | GlassVial or as required | |
How triptorelin works?
Triptorelin reduces female testosterone levels and female estrogen levels by preventing the release of luteinizing hormone from the pituitary gland and prevents the ovaries from producing estrogen.
Since prostate cancer is dependent on testosterone for growth, hormone therapy that lowers testosterone levels can slow the progression of cancer or reduce cancer.
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