Thyrotropin Releasing Peptide Steroid Hormones TRH Protirelin Acetate CAS 24305-27-9

Thyrotropin Releasing Peptide Steroid Hormones TRH Protirelin Acetate CAS 24305-27-9

Basic information:

Name: TRH (Thyrotropin Releasing Hormone)/Protirelin
Sequence: (pyro)Glu-His-Pro-NH2
Molecular formula: C16H22N6O4
Molar Mass: 362.38 g/mol
CAS number: 24305-27-9
PubChem: CID 439302
Purity: 98%
Appearance: white powder
Source: synthetic
Density: 1.3 g/cm3
Refractive Index: n20D 1.55

What is Protirelin ?
Protirelin is the pharmaceutically available synthetic analogue of the endogenous peptide thyrotropin-releasing hormone (TRH). It is a tri-peptide tropic hormone, released by the hypothalamus, that stimulates the release of Thyroid Stimulating Hormone (TSH) and prolactin from the anterior pituitary.

Although not currently available in any FDA-approved product, protirelin is a component of the TRH Test where it is used to test the response of the anterior pituitary gland in conditions such as secondary hypothyroidism and acromegaly.

Function

Store the kit at 4°C upon receipt.The kit should be equilibrat4ed to room temperature before the assay. Remove any unneeded strips from Human MUSK Antibody-Coated plate, reseal them in zip-lock foil and keep at 4°C.

Precipitates may appear in concentrated washing buffer. Please heat the buffer to dissolve all the precipitates, which will not affect the results.

Accurate pipette should be used to avoid experimental error. Samples should be added to the Microplate in less than 5 minutes. If a large number of samples are included, multiple channel pipette is recommended.

Standard curve should be included in every assay. Replicate wells are recommended. If the OD value of the sample is greater than the first well of standards, please dilute the sample (n times) before test. When calculating the original MUSK ?concentration, please multiply the total dilution factor (XnX5).

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