Pharmaceutical Female Anabolic Steroidss Powder Eplerenone CAS 107724 20 9

Pharmaceutical Female Anabolic Steroidss Powder Eplerenone CAS 107724 20 9

Eplerenone Basic Info

Product Name: Eplerenone
CAS: 107724-20-9
MF: C24H30O6
MW: 414.49
Assay: >98%
Appearance: White solid
Density: 1.31 g/cm3
Melting Point: 241-243 ° C
Boiling Point: 597.933 ° C at 760 mmHg
Flash Point: 259.474 ° C
Storage: Keep it under seal in cool and dark place

Eplerenone Application

Selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.

Eplerenone is an aldosterone antagonist with an IC50 of 0.36 μM. It is used as an adjunct in the management of chronic heart failure. It is similar to the diuretic spironolactone, though it may be more specific for the mineralocorticoid receptor.

Description:

Common adverse drug reactions (ADRs) associated with the use of eplerenone include: hyperkalaemia,

hypotension, dizziness, altered renal function, and increased creatinine concentration. Eplerenone may

have a lower incidence of sexual side effects such as feminization, gynecomastia, impotence, low sex

drive and reduction of size of male genitalia. Due to the high risk of elevated potassium levels in

individuals taking eplerenone, the United States FDA suggests routine checks on the individual's

potassium level to screen for hyperkalemia.

Eplerenone (INN) is an aldosterone antagonist used as an adjunct in the management of chronic heart

failure. It is similar to the diuretic spirono lactone, though it is much more selective for the

mineralocorticoid receptor in comparison (i.e., does not possess any antiandrogen, progestogen, or

estrogenic effects), and is specifically marketed for reducing cardiovascular risk in patients following

myocardial infarction. It is marketed by Pfi zer under the trade name Inspra. Eplerenone is a potassium-sparing diuretic, meaning that it helps the body get rid of water but still keep potassium.

Eplerenone COA

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