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Product Name: | Desloratadine | Cas: | 100643-71-8 |
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Appearance: | White Powder | Purity: | 99% |
Usage: | Relief Allergic Rhinitis | ||
High Light: | steroid raw powder,powder steroids |
CAS 100643-71-8 Desloratadine Raw Steroid Powder For Relief Allergic Rhinitis
Quick Detail:
Desloratadine
Product Name: Desloratadine
Synonyms: DESLORATADINE;DESLORATIDINE;8-chloro-6,11-dihydro-11-(4-piperdinylidene)-5h-benzo[5,6]cyclohepta[1,2-b]pyridine;8-CHLORO-6,11-DIHYDRO-11-(4-PIPERIDINYLIDENE)-5H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDINE;AKOS 92131;SCH-34117;Aerius;Dis-loratadine
CAS: 100643-71-8
MF: C19H19ClN2
MW: 310.82
Chemical Properties Beige Solid
Usage A histamine H1-receptor antagonist. An active metabolite of Loratadine
Usage Nonsedating-type histamine H1-receptor antagonist. An active metabolite of Loratadine. Also inhibits generation and release of inflammatory mediators from basophils and mast cells.
Usage antiinflammatory
Usage For the relief of symptoms of seasonal allergic rhinitis, perennial (non-seasonal) allergic rhinitis. Desloratidine is also used for the sympomatic treatment of pruritus and urticaria (hives) associated with chronic idiopathic urticaria.
Desloratadine Dosage:
Desloratadine,Adults and children over the age of 6 are typically given 10 mg of loratadine per day. This usually equates to two teaspoons or one tablet, but you should read the instructions on your package to make sure that this is the case for the brand you are working with. Children ages 2-5 should be limited to 5 mg or one teaspoon of the liquid form of loratadine per day. Children in this age group should not use loratadine tablets.
Desloratadine,Pregnant women may be able to use loratadine without risk to their fetus, but there are no scientific studies that confirm whether or not this is a risk. Talk with your doctor about this risk before you start using loratadine to ensure that the benefits will outweigh the risks. If you are breastfeeding you may need to avoid using loratadine because it can be transferred to your child through the breast milk, and children are at an increased risk for side effects when exposed to loratadine.
Desloratadine,Adults and children with liver failure or renal insufficiency may need to adjust their dosing to ensure that the drug is sufficiently clearing from your system before you take another dose. In most cases, this will mean taking the same sized dose recommended for your age group, but limiting your dosing to every other day. If you have any other concerns regarding how your doses should be administered, ask your doctor what kind of dosing schedule is appropriate for you.
Desloratadine Side Effects:
This drug usually has no side effects. If you have any unusual effects, contact your doctor or pharmacist promptly.
very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
COA:
ITEMS | STANDARD | RESULTS |
Characteristics | White or almost white crystalline powder | White crystalline powder |
Melting point | 175.0~177.0ºC | 174.0~179.0ºC |
Specific rotatlon | +128°±3(C=1,CH3OH) | +128°±3(C=1,CH3OH) |
Loss on drying | ≤0.5% | 0.32% |
Heavy metals | 0ppm | 0ppm |
Relative substance | ≤0.1% Total impurity |
0.07% |
Assay(on drled basis) | ≥99.5% | 99.61% |
Conclusion | It complies to prescrlbed enterprise standard |
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