Bodybuilding Human Growth Steroids Pentadecapeptide BPC 157 CAS 137525-51-0

Bodybuilding Human Growth Steroids Pentadecapeptide BPC 157 CAS 137525-51-0

Detail Information
Other name : Pentadecapeptide BPC 157 ; Booly Protection Compound 15
CAS: 137525-51-0
MF: C62H98N16O22
MW: 1419.53552
Specification: 2mg/vial
Appearance: White Lyophilized Powder
Method of Analysis: HPLC
Storage: Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18°C. Upon reconstitution of the peptide it should be stored at 4°C between 2-21 days and for future use below -18°C

Abstract

BPC 157 (Body Protection Compound-157) is a pentadecapeptide made up of 15 amino acids. The amino acids sequence in BPC 157 is similar to a portion of the human BPC amino acid sequence. Human BPC is found in the gastric juice. Experiments have shown that BPC 157 enhances the healing of wounds, including tendons wounds such as transected Achilles tendons of rats. The aim of this study was to investigate the probable mechanism that BPC 157 utilizes to accelerate the healing process in an injured tendon.

The study used two group of tendon explants of which one group was cultured in a BPC 157-containing medium while the other group was cultured in a medium lacking BPC 157. These cultures were thereafter examined for tendon fibroblasts outgrowths. Such outgrowths indicated tendon regeneration.The results revealed that the explants' outgrowth was significantly accelerated in the culture containing BPC 157 as compared to the culture lacking BPC 157.

Also, a MTT assay did show that BPC 157 does not directly affect cellular proliferation in a culture of rat-derived Achilles tendon. However, results also showed that BPC 157 significantly increased the survival of cells under oxidative stress. Furthermore, the Transwell filter migration assay showed that BPC 157 significantly increased in-vitro fibroblast migration in a dose-dependent fashion. Moreover, BPC 157 accelerated the dispersal of the fibroblasts in culture dishes in a dose-dependent manner.

Description:

BPC 157 is a pentadecapeptide, meaning that is comprised of a chain of 15 amino acids. It has

been determined to be a partial sequence of body protection compound (BPC) that can be

isolated from gastric juices located in animal test subjects.

Application:

Because BPC 157 has proven to be isolated from gastric juices, it should not be a surprise to

find that various scientific studies that have been conducted on animal test subjects have been

able to pinpoint several links between the peptide's presence and digestive tract functionality.

Specifically, it has been determined that BPC 157 exhibits the capacity to regulate and control

the manner in which the digestive tract can operate.

One of the ways that BPC 157 accomplishes this is through safeguarding the endothelium, which

is the thin layer of cells that line the blood vessels' interior surface. Another way the peptide

carries out regulatory function is by being a key factor in the process of angiogenesis; that is, the

process in which new blood vessels are formed from pre-existing blood vessels.

This latter process is further bolstered by BPC 157's ability to form granulation tissue; this term

references the new connective tissues and tiny blood vessels that develop on the surface of

wound, thus making the peptide an important piece to the overall wound healing process. Further

studies have also shown that the peptide's inherent functionality allows it to contain anti-

inflammatory properties. Additionally, these studies have determined that BPC 157 can also help

in the regulation and control of blood flow throughout an animal test subject's gastro-intestinal

tract.

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