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Melengestrol Acetate Pharmaceutical Ingredient Antineoplastic Agent CAS 2919 66 6

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Melengestrol Acetate Pharmaceutical Ingredient Antineoplastic Agent CAS 2919 66 6

Melengestrol Acetate Pharmaceutical Ingredient Antineoplastic Agent CAS 2919 66 6
Melengestrol Acetate Pharmaceutical Ingredient Antineoplastic Agent CAS 2919 66 6 Melengestrol Acetate Pharmaceutical Ingredient Antineoplastic Agent CAS 2919 66 6

Large Image :  Melengestrol Acetate Pharmaceutical Ingredient Antineoplastic Agent CAS 2919 66 6

Product Details:

Brand Name: RedBird

Payment & Shipping Terms:

Minimum Order Quantity: 10Grams
Price: Negotiated
Packaging Details: Foil Bag
Delivery Time: 3-7days after received payment
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 5000Kg Per Month
Detailed Product Description
Product Name: Melengestrol Acetate Cas: 2919-66-6
Appearance: White Powder Purity: 99%
Grade: Pharmaceutical Grade Usage: Women Use
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Melengestrol Acetate Pharmaceutical Ingredient Antineoplastic Agent CAS 2919 66 6

 

Melengestrol Acetate
Cas: 2919-66-6
Molecular formula: C25H32O4
Packing: 5KG/TIN,2TIN/CTN
Unit: KG
Quality Standards: USP31

 

 

Description:

 

Melengestrol (INN, BAN) is a steroidal progestin and antineoplastic agent which was never marketed.An acylated derivative, melengestrol acetate, is used as a growth promoter in animals
Progestogens are synthetic forms of the naturally occurring hormone, progesterone. Progesterone is produced by the corpus luteum . By negative feedback, it reduces pituitary function, thus preventing a female from coming into heat. When administered in conjunction with a luteolytic agent, such as PGF2a or estradiol valerate, progestogens can provide an effective means of resetting the cow's physiological clock. If the progestogen is administered for several days, an artificial corpus luteum can in effect be installed, which can be removed at the producer's discretion.

 

Specifications :

 

Analysis Report

 

Analysis Test Specification Result
Description Light Yellow crystalline powder,odorless Conforms
Solubility Easily soluble in water, unsoluble in ethanol Conforms
PH 6.0~7.5 6.9
Solution clarity and color solution should be clear and colorless Conforms
Related substances

5’CMP 0.3%

Simple impurity

Total other impurity

0.01%

0.03%

0.10%

Chloride 0.05% Conforms
Ammonium 0.05% Conforms
Fe 0.01% Conforms
Phosphate 0.10% Conforms
Loss on drying ≤6.0% 1.30%
Heavy metals 0.00% Conforms
Arsenide 0.00% Conforms
Bacterial Endotoxins 0.3EU/mg Conforms
Microbial Limit Conforms Conforms
Assay(on dried basis) ≥98.0% 99.50%
Conclusion: The results conform with CP2013

 

Melengestrol Acetate Pharmaceutical Ingredient Antineoplastic Agent CAS 2919 66 6 0

Application:

Melengestrol acetat is widely used as a growth promoting feed additive in cattle breeding in the USA and several other non-European countries. To explore the physiological effects of MGA four heifers were fed during 8 weeks with 0.5 mg MGA daily as registered in the USA and two heifers each received 0, 1.5 or 5 mg/day, respectively. Plasma samples were collected twice a week and concentrations of MGA, progesterone and estradiol-17beta were quantified. The pulsatile secretion of luteinizing hormone was investigated in 6-hour profiles before and during treatment. After slaughter the reproductive organs were examined and oestrogen residues in edible tissues were measured.

Four days after the beginning of MGA feeding MGA concentrations in plasma reached levels of 30 and 100-400 pg/mL depending on the dose received. Three weeks after the beginning of MGA feeding P4 plasma concentrations had dropped to base levels below 0.3 ng/mL in all three treatment groups. Mean plasma E2-17beta levels increased in physiological range from 1 to 5 pg/mL during 0.5 mg MGA/day feeding with many acyclic peaks. Overdosed MGA decreased E2 levels and suppressed cyclic peaks. Number and size of ovarian follicles were not altered by any treatment. Mean LH levels and pulse frequencies increased significantly during labelled treatment , while higher doses had reducing effects. The development of corpus luteum was suppressed. E2-17beta residues in fat increased about 300% following labelled MGA treatment.

Melengestrol Acetate Pharmaceutical Ingredient Antineoplastic Agent CAS 2919 66 6 1

 

Competitive Advantage:

 

1) We specialize in this field for 9 year, have rich experience.
2) The purity of our product are all over 99%
3) Because we are factory direct sale, so we can give you a better price.
4) All the parcel can be sent in 24 hours after the payment, we guarantee 100% safe delivery.
5) We have the strong and effective courier, they are experience on safe delivery.
6) We have the best After-Sale department to provide you the great service.
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