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CAS 566 48 3 Estrogen Steroid Raws Formestane For Breast Cancer Treatment Lentaron

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CAS 566 48 3 Estrogen Steroid Raws Formestane For Breast Cancer Treatment Lentaron

CAS 566 48 3 Estrogen Steroid Raws Formestane For Breast Cancer Treatment Lentaron
CAS 566 48 3 Estrogen Steroid Raws Formestane For Breast Cancer Treatment Lentaron CAS 566 48 3 Estrogen Steroid Raws Formestane For Breast Cancer Treatment Lentaron

Large Image :  CAS 566 48 3 Estrogen Steroid Raws Formestane For Breast Cancer Treatment Lentaron

Product Details:

Brand Name: RedBird

Payment & Shipping Terms:

Minimum Order Quantity: 10Grams
Price: Negotiated
Packaging Details: Foil Bag
Delivery Time: 3-7days after received payment
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 5000KG Per Month
Detailed Product Description
Product Name: Formestane Cas: 566-48-3
Purity: 99% Appearance: White Powder
Usage: Breast Cancer Treatment
High Light:

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CAS 566 48 3 Estrogen Steroid Raws Formestane For Breast Cancer Treatment Lentaron

 

Formestane/Lentaron Basic Info:

Product Name:Formestane
CAS No: 566-48-3
Einecs No: 219-112-8
MF: C19H26O3
MW: 302.41.
Purity: 99.3%
Appearance: white crystalline powder

Formestane/Lentaron COA

Product Name Formestane
Production Bath 20190312 Production Date 2019/3/12
Specification Enterprise Standard Shelf life 2 Years
Quantity 100kg Analysis Date 2022/5/12
Result For Analysis
Items Standard Results
Test Specification Results
Appearance White or Almost White Crystalline Powder Conforms
Melting Point 199-203℃ 201.5℃
Loss On Drying 0.50% 0.32%
Specific Rotation +172~+182° +174.5 ~+181°
Assay not less than 97% 99.80%
Conclusion Conforms Specifications of Enterprise Standard.

 

CAS 566 48 3 Estrogen Steroid Raws Formestane For Breast Cancer Treatment Lentaron 0

 

Description:

 

Formestane Is the second generation of irreversible steroid aromatase inhibitors. It inhibits the aromatase responsible for converting androgen into estrogen, thereby preventing estrogen production. Breast cancer may be estrogen-sensitive or insensitive. Most breast cancers are estrogen-sensitive. Estrogen-sensitive breast cancer cells are dependent on estrogenic activity. Therefore, removal of estrogen from the body can become an effective treatment for hormone-sensitive breast cancer.

 

Formestane is dedicated to the treatment of postmenopausal women. Unlike premenopausal women who produce the most estrogen in the ovaries, postmenopausal women produce most estrogens in peripheral tissues with the help of aromatases. Methanesulfonamide aromatase inhibitors can help reduce the production of estrogen by blocking aromatase (ie, attached to mammary gland tissue) in peripheral tissues to treat hormone-sensitive breast cancer.

 

Formestane is Also known as lentaron, is an anti-cancer drug, mainly used for the treatment of advanced breast cancer in postmenopausal women, also effective for prostate cancer.

 

Methanesulfonic acid is a androstenedione derivative, an aromatic enzyme inhibitor with amino hydroxyethyl amide, is a hormone antineoplastic agent. Under physiological conditions, it may competitively inhibit the synthesis of enzymes, resulting in reduced estrogen biosynthesis in the tissue, and then it works in cancer. When tumor tissue growth depends on the presence of estrogen, it is necessary to eliminate tumor estrogen-mediated growth stimuli in order to inhibit tumor growth.

 

The product is more selective than amino isoflavones, and its activity is amino-hydroxyethylamine 100 to 1000 times, does not inhibit the synthesis of adrenal hormones, without the need to add cortisone and so on. The in vitro inhibition of the product's aromatase is 60 times stronger than that of aminosuccinimide.

 

When it is used alone, when it is combined with goserelin (gonadotropin-releasing hormone agonist), the drug does not significantly reduce premenopausal estrogen levels in women's blood, and estrogen inhibition in premenopausal women The effect is greater than that of goserelin alone using methanesulfonic acid with other aromatase inhibitors without cross resistance, which does not have side effects of aminoglucan.

 

After oral administration, it is rapidly absorbed by the gastrointestinal tract, the plasma concentration of the peak time of 1 ~ 1.5 hours, but the individual peak concentration difference; intramuscular injection, can be accumulated in the injection site and slowly absorbed. It performs a biphasic elimination process, the initial elimination half-life of 2 to 4 days, the terminal elimination half-life of 5 to 10 days. After oral administration mainly in the liver metabolism, uridine excretion of glycoside metabolites in the form of existence.

 

Applications:

Formestane is a second generation, irreversible, steroidal aromatase inhibitor. It inhibits the aromatase enzyme responsible for converting androgens to estrogens, thereby preventing estrogen production. Breast cancer may be estrogen sensitive or insensitive. A majority of breast cancers are estrogen sensitive. Estrogen sensitive breast cancer cells depend on estrogen for viability.

Thus removal of estrogen from the body can be an effective treatment for hormone sensitive breast cancers. Formestane has been targeted specifically for the treatment of postmenopausal women. Unlike premenopausal women who produce most estrogen in the ovaries, postmenopausal women produce most estrogen in peripheral tissues with the help of the aromatase enzyme. Formestane, an aromatase inhibitor, can thus help to decrease the local production of estrogen by blocking the aromatase enzyme in peripheral tissues (ie. Adispose tissue of the breast) to treat hormone sensitive breast cancer.

CAS 566 48 3 Estrogen Steroid Raws Formestane For Breast Cancer Treatment Lentaron 1

 

The Product List

 
Product Name CAS No.
 

Testosterone Series

Testosterone 58-22-0
Testosterone Enanthate 315-37-7
Testosterone Acetate 1045-69-8
Testosterone Cypionate 58-20-8
Testosterone Propionate 57-85-2
Testosterone Phenylpropionate 1045-69-8
Testosterone Isocaproate 15262-86-9
Testosterone Decanoate 5721-91-5
Sustanon 250  
Sustanon 100  
Testosterone undecanoate 5949-44-0
Oral turinabo(4-Chlorodehydromethyltestosterone) 2446-23-3
4-Chlorotestosterone acetate (Clostebol acetate) 855-19-6
Mestanolone 521-11-9
Stanolone (androstanolone) 521-18-6
Mesterolone (Proviron) 1424-00-6
Fluoxymesterone 76-43-7
 

Nandrolone Series

Nandrolone 434-22-0
Nandrolone Decanoate 360-70-3
Nandrolone Phenylpropionate(Durabolin) 62-90-8
Nandrolone Undecylenate 862-89-5
Nandrolone propionate 7207-92-3
Nandrolone Cypionate  
Trenbolone series  
Trenbolone Acetate (Finaplix H/Revalor-H) 10161-34-9
Trenbolone Enanthate(parabola) 10161-33-8
Methyltrienolone 965-93-5
Trenbolone Hexahydrobenzyl Carbonate 23454-33-3
Tibolone 5630-53-5
 

Boldone series

Boldenone Undecylenate (Equipoise) 13103-34-9
Boldenone 846-48-0
boldenone cypionate 106505-90-2
boldenone Acetate 2363-59-9
Boldenone propionate  
 

DHEA series

Dehydroisoandrosterone 3-acetate 853-23-6
Dehydroepiandrosterone (DHEA) 53-43-0
Epiandrosterone 481-29-8
7-keto DHEA 566-19-8
Drostanolone Series
Superdrol Powder (Methyl-drostanolone) 3381-88-2
Drostanolone enanthate 472-61-145
Drostanolone Propionate 521-12-0
Methenolone Series  
Methenolone enanthate 303-42-4
methenolone acetate 434-05-9
 

Oral Steroids

Methandrostenolone (Dianabol, methandienone) 72-63-9
Oxymetholone(Anadrol) 434-07-1
Stanozolol (Winstrol) 710418-03-8
Oxandrolone (Anavar) 53-39-4
 

Antiestrogen Series

Tamoxifen Citrate 54965-24-1
Clomiphene Citrate(Clomid) 50-41-9
Tamoxifen Citrate (Nolvadex) 54965-24-1
Toremifene Citrate(Fareston) 89778-27-8
Exemestane 107868-30-4
Anastrozole (arimidex) 120511-73-1
Letrozole 112809-51-5
Fulvestrant 129453-61-8
 

Sex Enhancers

Tadalafil (Cialis) 171596-29-5
Sildenafil (Viagra) 139755-83-2
Vardenafil 224789-15-5
Yohimbine HCl 65-19-0

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