WuHan RedBird Biotech Co,Ltd.

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443 48 1 Pharmaceutical Raw Materials Metronidazole Flagyl Treat Bacterial Infections

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443 48 1 Pharmaceutical Raw Materials Metronidazole Flagyl Treat Bacterial Infections

443 48 1 Pharmaceutical Raw Materials Metronidazole Flagyl Treat Bacterial Infections
443 48 1 Pharmaceutical Raw Materials Metronidazole Flagyl Treat Bacterial Infections 443 48 1 Pharmaceutical Raw Materials Metronidazole Flagyl Treat Bacterial Infections

Large Image :  443 48 1 Pharmaceutical Raw Materials Metronidazole Flagyl Treat Bacterial Infections

Product Details:

Brand Name: RedBird

Payment & Shipping Terms:

Minimum Order Quantity: 100Grams
Price: Negotiated
Packaging Details: Foil Bag
Delivery Time: 3-7days after received payment
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 5000Kg Per Month
Detailed Product Description
Product Name: Metronidazole Alias: Flagyl
Purity: 99% Appearance: White Powder
Grade: Pharmaceutical Usage: Treat Bacterial Infections
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443 48 1 Pharmaceutical Raw Materials Metronidazole Flagyl Treat Bacterial Infections

 

Basic Info

Synonyms: trans-4-Aminomethylcyclohexane-1-carboxylate; trans-4-(Aminomethyl)cyclohexanecarboxylic acid; Amstat; amcha; trans-cyclohexanecarboxylic acid;

CAS: 443-48-1

EINECS: 207-136-1

MF: C6H9N3O3

MW: 171.154

Assay: 99% min

Melting point: 300℃

Standard: BP/EP/USP

Packing: 25kg/cardboard drum.

Character: White crystalline powder.

443 48 1 Pharmaceutical Raw Materials Metronidazole Flagyl Treat Bacterial Infections 0

 

Pharmacology
In addition to anti-trichomonas and anti-amoeba, in recent years, widely used in anti-anaerobic infections. This product nitro, anaerobic environment in the reduction of amino and anti-anaerobic bacteria show the role of aerobic bacteria or facultative aerobic bacteria is invalid. The following anaerobic bacteria have good antibacterial effect: ① Bacteroides, including Bacteroides fragilis; ② Fusobacterium; ③ Clostridium, including tetanus; ④ partial eubacteria; ⑤ digestive bacteria and digestion Streptococcus and so on. Oral absorption of good (> 80%), oral 250mg or 500mg, 1 ~ 2 hours serum drug concentration peak, respectively 6μg / ml and 12μg / ml. Intravenous infusion of the goods 15mg / kg, after every 6 hours infusion of 7.5mg / kg, plasma drug concentration reached a peak concentration of 25μg / ml, trough concentration of up to 18μg / ml. This product is widely distributed in the body, can enter the saliva, milk, liver abscess pus, can also enter the cerebrospinal fluid (normal CSF concentration of up to 50% of blood). In the body, the side chain oxidation or metabolism with glucuronic acid binding, 20% of the drug is not metabolized. Its metabolites also have a certain activity. Metronidazole and its metabolites by a large number of urinary excretion (60% of the total ~ 80%), a small amount of excretion from the feces (6% ~ 15%). T1 / 2 is about 8 hours.

 

Indications
Mainly for the treatment or prevention of anaerobic bacteria caused by the system or local infection, such as the abdominal cavity, digestive tract, female genital tract, lower respiratory tract, skin and soft tissue, bone and joint parts of anaerobic infections, sepsis, Membranitis, meningeal infection and the use of antibiotics caused by colitis is also effective. Treatment of tetanus and tetanus antitoxin (TAT) in combination. Can also be used for oral anaerobic infections.

 

Certificate of Analysis

Name of product: Metronidazole
Expiry Date: 4 years
ITEMS STANDARDS RESULTS
Characteristics a white or yellowish crystalline powder, slighting sobube in water, in acetone, in alcohol and in methylene, chloride, very slightly solube in ether COMPLY
Identification a) Melting point 159-163℃ 161.1-161.3℃
b) Specific absorbance 365-395 b) 375
c) IR c) COMPLY
d) The solution gives the reaction of primary aromatic amines d) COMPLY
Appearance of solution SUSPENSION Ⅱ COMPLY
AND SOLUTION GY6
Related substances Impurity:0.1MAX 0.02%
Total impurity:0.2MAX 0.06%
Heavy Metal 20PPM MAX <20PPM
Loss on drying 0.5% MAX 0.19%
Particle size 40-80mesh COMPLY
Assay 99.0%-101.0% 99.4%


Functions

1. Mainly used to treat or prevent systemic or local infections caused by the above-mentioned anaerobic bacteria, such as in the abdomen, digestive tract, female reproductive system, lower respiratory tract, skin and soft tissue, bone and joints
2. Also effective for septicemia, endocarditis, meningeal infection and colitis due to antibiotic use.
3. The treatment of tetanus is often combined with tetanus antitoxin(TAT). It can also be used for oral anorexia infection.

443 48 1 Pharmaceutical Raw Materials Metronidazole Flagyl Treat Bacterial Infections 1

Packaging Details:

1. 1kg Aluminum Foil Bag.

2. Standard packed In fiber-drums with two-plastic bags inside.
Wight: Net weight 25kg/drum; gross weight 28kg/drum
Drum Size & Volume: I.D.37cm x H51cm, 0.070cubic meter/ drum

3. As customer's requested.

 

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